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Prostate Cancer Screening Guidelines Revised by American Cancer Society

The American Cancer Society has revised its guidelines for prostate cancer screening, recommending that all men undergo routine testing using a PSA test.

In reversal, American Cancer Society urges prostate cancer tests for all men
Source: Ars Technica

The American Cancer Society has issued new guidelines for prostate cancer screening, recommending that all men undergo routine testing using a PSA test.

Men at average risk of developing prostate cancer should receive a PSA test every two years between the ages of 50 and 69, according to the updated recommendations released this week. This is a significant shift from previous guidelines, which may have had varying requirements for different demographics.

The new guidelines also recommend earlier testing for men considered high-risk due to their racial background or family history. Specifically, Black men are advised to start yearly PSA testing at age 45, as they are more susceptible to developing prostate cancer than other demographics.

In addition to race, the Society has taken into account a person's genetic predisposition to prostate cancer when determining screening recommendations. Non-Black men with a close relative diagnosed with prostate cancer before the age of 65 or multiple relatives affected by the disease should also begin yearly testing at 45.

Men aged between 70 and 74 are being advised to consult their doctors about continuing PSA screenings, while those over 75 are no longer recommended for routine testing.

The American Cancer Society has revised its stance on prostate cancer screenings, now recommending routine tests for all men without age restrictions. This change is a departure from its previous guidelines, which were published in 2010 and did not make universal recommendations for screening.

The new guidance is based on emerging evidence that shows regular screenings can save lives. Studies have also shown that advances in case management can minimize the risks associated with overdiagnosis and overtreatment. In fact, many men diagnosed with prostate cancer will never experience any symptoms or harm from their condition.

The ACS has added a layer of caution to its new guidelines by advising all men to be aware of the potential benefits and drawbacks of screening. If a PSA test results in a high reading, defined as 3 ng/mL or higher for men under 70, and 6.5 ng/mL or higher for those aged 70 and above, the organization recommends repeating the test before taking any further action.

The ACS's updated stance on prostate cancer screenings comes at a time when other health organizations are also re-examining their recommendations. The US Preventive Services Task Force is currently working on an update to its own guidance, but it has faced controversy in recent months due to concerns about conflicts of interest among its new members.

The ACS's decision to recommend routine prostate cancer screenings for all men without age restrictions reflects a growing understanding of the benefits and risks associated with early detection. By providing more comprehensive guidelines, the organization aims to help men make informed decisions about their health.

A new approach is being recommended for prostate cancer testing by a leading health organization. According to its guidelines, men who have had previous negative results but still undergo frequent tests should consider either an MRI or a validated biomarker test to assess their risk level.

The goal of this revised strategy is to reduce unnecessary procedures and treatments while ensuring that those with aggressive cancers are identified and treated promptly. This would involve reserving biopsies for cases where there is a high suspicion of cancer, such as in men with very high PSA test results.

For men diagnosed with low-risk prostate cancer, active surveillance should be the initial management strategy. As Dr. Shanthi Sivendran notes, "By catching aggressive cancers with a simple PSA blood test, you open the door to highly effective treatments that protect your future."

Facts based on reporting originally published by Ars Technica.

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